International peer-reviewed publications
2019
Vannini P, d'Oleire Uquillas F, Jacobs HIL, Sepulcre J, Gatchel J, Amarillo RE, Hanseeuw B, Papp KV, Hedden T, Rentz DM, Pascual-Leone A, Johnson KA, Sperling RA (2019). Decreased meta-memory is associated with is early tauopathy in cognitively unimpaired older individuals. Neuroimage Clinical, accepted (IF 3.943)
Riphagen JM, Ramakers IHGM, Freeze WM, Pagen LHG, Hanseeuw BJ, Verbeek MM, Verhey FRJ, Jacobs HIL (2019). Linking APOE-E4, blood-brain barrier dysfunction and inflammation to Alzheimer's pathology. Neurobiology of Aging, accepted (IF 4.454)
Freeze WM, Jacobs HIL, de Jong JJ, Verheggen ICM, Gronenschild EHBM, Palm WM, Hoff EI, Wardlaw JM, Jansen JFA, Verhey FRJ, Backes WH (2019). White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed. Neurobiology of Aging, accepted (IF 4.454)
d'Oleire Uquillas F, Jacobs HIL, Schultz AP, Hanseeuw BJ, Buckley RF, Sepulcre J, Pascual-Leone A, Donovan NJ, Johnson KA, Sperling RA, Vannini P (2019). Functional and pathological correlates of judgments of learning in cognitively unimpaired older adults. Cerebral Cortex, accepted. (IF 5.437)
Duecker F, Mayrhofer HC, Jacobs HIL, Sack AT (2019). No effect of cold pressor test-induced arousal on attentional benefits and costs in an endogenous spatial orienting paradigm. Neuropsychologia, accepted.(IF 2.872)
Jacobs HIL. Focus on the blue locus for learning. Nature Human Behaviour, accepted. (IF 10.586)
Richter N, Nellessen N, Dronse J, Dillen K, Jacobs HIL, Langen KJ, Dietlein M, Kracht L, Neumaier B, Fink GR, Kukolja J, Onur OA (2019). Spatial distributions of cholinergic impairment and neuronal hypo metabolism differ in MCI due to AD. Neuroimage Clinical, accepted (IF 3.943)
Priovoulos N, Poser BA, Ivanov D, Verhey FR, Jacobs HIL. (2019). In vivo imaging of the nucleus of the solitary tract with Magnetization Transfer at 7 Tesla. Neuroimage, accepted (IF 5.812)
Freeze WM, Ter Weele DN, Palm WM, van Horen RW, Hoff EI, Jansen JFA, Jacobs HIL, Verhey FR, Backes WH. (2019) Optimal detection of subtle gadolinium leakage in CSF with heavily T2-weighted Fluid-Attenuated Inversion Recovery Imaging, American Journal of Neuroradiology, accepted (IF 3.256)
Betss MJ, Kirilina E, Otaduy M, Ivanov D, Acosta-Cabronero J, Callaghan M Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu K, Priovoulos N, Fliessbach K, Dahl MJ, Maass A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner H, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E*, Hämmerer D* (2019). Locus coeruleus imaging as a biomarker for neurodegeneration. Brain, accepted (IF 11.814).
Song TA, Roy Chowdhury S, Yang F, Jacobs HIL, El Fakhri G, Li Q, Johnson KA, Dutta J. (2019). Graph convolutional neural networks for Alzheimer's disease classification. Proc IEEE Int Symp Biomed Imag, 414-419.
Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rente DM, Johnson KA, Sperling RA, Donovan NJ (2019). Social engagement and amyloid-beta related cognitive decline in cognitively normal older adults. American Journal of Geriatric Psychiatry, accepted (IF 3.488)
Bischof GN, Jacobs HIL. (2019) Subthreshold amyloid and its biological and clinical meaning. Neurology. accepted (IF 8.689)
Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedder T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson KA (2019). Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study. JAMA Neurology, accepted (IF 12.321)
Jacobs HIL, Riphagen JM, Ramakers IHGB, Verhey FRJ. (2019). Alzheimer's disease pathology: pathways between central norepinephrine activity, memory and neuropsychiatric symptoms. Molecular Psychiatry. accepted (IF 11.973)
Yang F, Roy Chowdhury S, Jacobs HIL, Johnson KA, Dutta J (2019). A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity. Inf Process Med Imaging, 11492, 384-393.
Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs HIL, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ (2019). Associations between baseline amyloid, sex and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging, 78, 178-185 (IF 4.398)
Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzman-Velez E, Jacobs HIL, Hanseeuw B, Padilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT (2019). Biological and cognitive markers of Presenilin1 E280A Autosomal Dominant Alzheimer's disease: a comprehensive review of the Colombian kindred. The Journal of Prevention of Alzheimer's disease, 6(2), 112-120..
Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, Price J, Chhatwal J, Rentz DM, Villemagne VL, Johnson KA, Sperling RA. (2019). Sex differences in the association between global amyloid and regional tau deposition measured by positron emission tomography in clinically normal older adults. JAMA Neurology, accepted (IF 12.321)
Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ. (2019). Blood-brain barrier leakage and microvascular lesions in Cerebral Amyloid Angiopathy. Stroke, 50(2),328-335 (IF 6.046)
Riphagen JM, Ramakers IHGM, Freeze WM, Pagen LHG, Hanseeuw BJ, Verbeek MM, Verhey FRJ, Jacobs HIL (2019). Linking APOE-E4, blood-brain barrier dysfunction and inflammation to Alzheimer's pathology. Neurobiology of Aging, accepted (IF 4.454)
Freeze WM, Jacobs HIL, de Jong JJ, Verheggen ICM, Gronenschild EHBM, Palm WM, Hoff EI, Wardlaw JM, Jansen JFA, Verhey FRJ, Backes WH (2019). White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed. Neurobiology of Aging, accepted (IF 4.454)
d'Oleire Uquillas F, Jacobs HIL, Schultz AP, Hanseeuw BJ, Buckley RF, Sepulcre J, Pascual-Leone A, Donovan NJ, Johnson KA, Sperling RA, Vannini P (2019). Functional and pathological correlates of judgments of learning in cognitively unimpaired older adults. Cerebral Cortex, accepted. (IF 5.437)
Duecker F, Mayrhofer HC, Jacobs HIL, Sack AT (2019). No effect of cold pressor test-induced arousal on attentional benefits and costs in an endogenous spatial orienting paradigm. Neuropsychologia, accepted.(IF 2.872)
Jacobs HIL. Focus on the blue locus for learning. Nature Human Behaviour, accepted. (IF 10.586)
Richter N, Nellessen N, Dronse J, Dillen K, Jacobs HIL, Langen KJ, Dietlein M, Kracht L, Neumaier B, Fink GR, Kukolja J, Onur OA (2019). Spatial distributions of cholinergic impairment and neuronal hypo metabolism differ in MCI due to AD. Neuroimage Clinical, accepted (IF 3.943)
Priovoulos N, Poser BA, Ivanov D, Verhey FR, Jacobs HIL. (2019). In vivo imaging of the nucleus of the solitary tract with Magnetization Transfer at 7 Tesla. Neuroimage, accepted (IF 5.812)
Freeze WM, Ter Weele DN, Palm WM, van Horen RW, Hoff EI, Jansen JFA, Jacobs HIL, Verhey FR, Backes WH. (2019) Optimal detection of subtle gadolinium leakage in CSF with heavily T2-weighted Fluid-Attenuated Inversion Recovery Imaging, American Journal of Neuroradiology, accepted (IF 3.256)
Betss MJ, Kirilina E, Otaduy M, Ivanov D, Acosta-Cabronero J, Callaghan M Lambert C, Cardenas-Blanco A, Pine K, Passamonti L, Loane C, Keuken MC, Trujillo P, Lüsebrink F, Mattern H, Liu K, Priovoulos N, Fliessbach K, Dahl MJ, Maass A, Madelung CF, Meder D, Ehrenberg AJ, Speck O, Weiskopf N, Dolan R, Inglis B, Tosun D, Morawski M, Zucca FA, Siebner H, Mather M, Uludag K, Heinsen H, Poser BA, Howard R, Zecca L, Rowe JB, Grinberg LT, Jacobs HIL, Düzel E*, Hämmerer D* (2019). Locus coeruleus imaging as a biomarker for neurodegeneration. Brain, accepted (IF 11.814).
Song TA, Roy Chowdhury S, Yang F, Jacobs HIL, El Fakhri G, Li Q, Johnson KA, Dutta J. (2019). Graph convolutional neural networks for Alzheimer's disease classification. Proc IEEE Int Symp Biomed Imag, 414-419.
Biddle KD, Uquillas FD, Jacobs HIL, Zide B, Kirn DR, Rente DM, Johnson KA, Sperling RA, Donovan NJ (2019). Social engagement and amyloid-beta related cognitive decline in cognitively normal older adults. American Journal of Geriatric Psychiatry, accepted (IF 3.488)
Bischof GN, Jacobs HIL. (2019) Subthreshold amyloid and its biological and clinical meaning. Neurology. accepted (IF 8.689)
Hanseeuw BJ, Betensky RA, Jacobs HIL, Schultz AP, Sepulcre J, Becker JA, Cosio DMO, Farrell M, Quiroz YT, Mormino EC, Buckley RF, Papp KV, Amariglio RA, Dewachter I, Ivanoiu A, Huijbers W, Hedder T, Marshall GA, Chhatwal JP, Rentz DM, Sperling RA, Johnson KA (2019). Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study. JAMA Neurology, accepted (IF 12.321)
Jacobs HIL, Riphagen JM, Ramakers IHGB, Verhey FRJ. (2019). Alzheimer's disease pathology: pathways between central norepinephrine activity, memory and neuropsychiatric symptoms. Molecular Psychiatry. accepted (IF 11.973)
Yang F, Roy Chowdhury S, Jacobs HIL, Johnson KA, Dutta J (2019). A longitudinal model for tau aggregation in Alzheimer's disease based on structural connectivity. Inf Process Med Imaging, 11492, 384-393.
Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs HIL, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ (2019). Associations between baseline amyloid, sex and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiology of Aging, 78, 178-185 (IF 4.398)
Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzman-Velez E, Jacobs HIL, Hanseeuw B, Padilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, Sperling RA, Reiman EM, Lopera F, Quiroz YT (2019). Biological and cognitive markers of Presenilin1 E280A Autosomal Dominant Alzheimer's disease: a comprehensive review of the Colombian kindred. The Journal of Prevention of Alzheimer's disease, 6(2), 112-120..
Buckley RF, Mormino EC, Rabin JS, Hohman TJ, Landau S, Hanseeuw BJ, Jacobs HIL, Papp KV, Amariglio RE, Properzi MJ, Schultz AP, Kirn D, Scott MR, Hedden T, Farrell M, Price J, Chhatwal J, Rentz DM, Villemagne VL, Johnson KA, Sperling RA. (2019). Sex differences in the association between global amyloid and regional tau deposition measured by positron emission tomography in clinically normal older adults. JAMA Neurology, accepted (IF 12.321)
Freeze WM, Bacskai BJ, Frosch MP, Jacobs HIL, Backes WH, Greenberg SM, van Veluw SJ. (2019). Blood-brain barrier leakage and microvascular lesions in Cerebral Amyloid Angiopathy. Stroke, 50(2),328-335 (IF 6.046)
2018
Wolters A.F., van de Weijer S.C.F., Leentjens A.F.G., Duits A.A., Jacobs H.I.L., Kuijf M.L. (2018). Resting-state fMRI in Parkinson's disease patients with cognitive impairment: a meta-analysis. Parkinsonism & Related Disorders, accepted (IF 4.360)
Sperling R.A., Mormino E.C., Schultz A.P., Betensky R.A., Papp K.V., Amariglio R.E., Hanseeuw B.J., Buckley R., Chhatwal J, Hedden T., Marshall G.A., Quiroz Y.T., Donovan N.J., Jackson J., Gatchel J.R., Rabin J.S., Jacobs H., Yang H.S., Properzi M., Kirn D.R., Rentz D.M., Johnson K.A.. (2018). The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology, 85 (2), 181-193 (IF: 9.496)
d'Oleire Uquillas F., Jacobs H.I.L., Biddle K.D., Properzi M., Hanseeuw B., Schultz A.P., Rentz D.M., Johnson K.A., Sperling R.A., Donovan N.J. (2018). Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry, 8(1), 282 (IF: 5.182)
Freeze WM, Jacobs HIL, Schreuder FHBM, van Oostenbrugge RJ, Backes WH, Verhey FR, Klijn CJM (2018). Blood-Brain Barrier dysfunction in small vessel disease related intracerebral hemorrhage. Frontiers Neurology, 9, 926 (2.635)
Jacobs H.I.L., Buckley R.F. (2018).. Where do white matter alterations dovetail with the cascade model of Alzheimer's disease? Brain. 141 (10), 2830-2833 (IF 11.814)
Sepulcre J, Grothe MH, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. (2018). Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine, 24(12), 1910-1918 (IF 30.641).
Bachmann C, Jacobs HIL, Porta Mana P, Dillen K, Richter N, von Reutern B, Dronse J, Onur OA, Langen KJ, Fink GR, Kukolja J, Morrison A. (2018). On the extraction and analysis of graphs from resting-state fMRI to support a correct and robust diagnostic tool for Alzheimer's disease. Frontiers in Neuroscience, 12, 528 (IF 3.648).
Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL (2018). Alzheimer's disease biomarkers have distinct associations with specific hippocampal subfield volumes. Journal Of Alzheimer's Disease, 66(2), 811-823 (IF 3.517)
Rienäcker F, Jacobs HIL, Van Heighten CM, Van Gerven PWM (2018). Practice makes perfect: high performance gains in older adults engaged in selective attention within and across sensory modalities. Acta Psychologica. 191, 101-111. (IF 1.595)
Mayrhofer HC, Duecker F, van de Ven V, Jacobs HIL, Sack AT (2018). Hemifield-specific correlations between cue-related blood oxygen level dependent activity in bilateral nodes of the dorsal attention network and attentional benefits in a spatial orienting paradigm. Journal of Cognitive Neuroscience. 21, 1-14 (IF 3.029)
van Hooren RWE, Riphagen JM, Jacobs HIL (2018). Internetwork connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer's disease: a longitudinal cohort study. Alzheimer's Research and Therapy, 10:88 (IF 6.142)
Rosenberg J, Jacobs HIL, Maximov II, Reske M, Shah J (2018). Chronotype differences in cortical thickness: grey matter reflects when you go to bed. Brain Structure and Function, 223(7), 3411-3421 (IF 3.622)
Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, Maruff P, Donohue MC, Rente DM, Kirn D, Hedden T, Chhatwal JP, Schultz AP, Johnson KA, Villemagne VL, Sperling RA, on behalf of collaborators in the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarker and Lifespan Study of Aging, the Harvard Aging Brain Study. (2018) Sex, amyloid and APOE-E4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia, 14(9), 1193-1203 (IF 14.423)
Jacobs HIL, Müller-Ehrenberg L, Priovoulos N, Roebroeck A. (2018) Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study. Neurobiology of Aging, 69, 167-176 (IF 4.398)
Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint M, Vannini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, for the Alzheimer's Disease Neuroimaging Initiative and the Harvard Aging Brain Study. (2018) PET staging of amyloidosis using striatum. Alzheimer's & Dementia, 14(10), 1281-1292 (IF 14.423)
Riphagen JM, Gronenschild EHBM, Salat DH, Freeze WM, Ivanov D, Clerx L, Verhey FRJ, Aalten P, Jacobs HIL (2018). Shades of white: diffusion properties of T1- and FLAIR defined white matter signal abnormalities differ in stages from cognitively normal to dementia. Neurobiology of Aging, 68, 48-58 (IF 4.398)
Lee CM*, Jacobs HIL*, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA (2018). 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus signal. Journal Of Alzheimer's Disease, 62, 1691-1702 (IF 3.517)
Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA & Johnson KA (2018). Structural tract alterations predict down-stream tau accumulation in amyloid positive older individuals. Nature Neuroscience, 21(3), 424-431 (IF 21.126)
Jacobs H.I.L., Hopkins D.A., Mayrhofer H.C., Bruner E., van Leeuwen F.W., Raaijmakers W. & Schmahmann J.D. (2017). The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline. Brain, 141(1), 37-47 (IF 11.814)
Sperling R.A., Mormino E.C., Schultz A.P., Betensky R.A., Papp K.V., Amariglio R.E., Hanseeuw B.J., Buckley R., Chhatwal J, Hedden T., Marshall G.A., Quiroz Y.T., Donovan N.J., Jackson J., Gatchel J.R., Rabin J.S., Jacobs H., Yang H.S., Properzi M., Kirn D.R., Rentz D.M., Johnson K.A.. (2018). The impact of Aβ and tau on prospective cognitive decline in older individuals. Annals of Neurology, 85 (2), 181-193 (IF: 9.496)
d'Oleire Uquillas F., Jacobs H.I.L., Biddle K.D., Properzi M., Hanseeuw B., Schultz A.P., Rentz D.M., Johnson K.A., Sperling R.A., Donovan N.J. (2018). Regional tau pathology and loneliness in cognitively normal older adults. Translational Psychiatry, 8(1), 282 (IF: 5.182)
Freeze WM, Jacobs HIL, Schreuder FHBM, van Oostenbrugge RJ, Backes WH, Verhey FR, Klijn CJM (2018). Blood-Brain Barrier dysfunction in small vessel disease related intracerebral hemorrhage. Frontiers Neurology, 9, 926 (2.635)
Jacobs H.I.L., Buckley R.F. (2018).. Where do white matter alterations dovetail with the cascade model of Alzheimer's disease? Brain. 141 (10), 2830-2833 (IF 11.814)
Sepulcre J, Grothe MH, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA. (2018). Neurogenetic contributions to amyloid beta and tau spreading in the human cortex. Nature Medicine, 24(12), 1910-1918 (IF 30.641).
Bachmann C, Jacobs HIL, Porta Mana P, Dillen K, Richter N, von Reutern B, Dronse J, Onur OA, Langen KJ, Fink GR, Kukolja J, Morrison A. (2018). On the extraction and analysis of graphs from resting-state fMRI to support a correct and robust diagnostic tool for Alzheimer's disease. Frontiers in Neuroscience, 12, 528 (IF 3.648).
Müller-Ehrenberg L, Riphagen JM, Verhey FRJ, Sack AT, Jacobs HIL (2018). Alzheimer's disease biomarkers have distinct associations with specific hippocampal subfield volumes. Journal Of Alzheimer's Disease, 66(2), 811-823 (IF 3.517)
Rienäcker F, Jacobs HIL, Van Heighten CM, Van Gerven PWM (2018). Practice makes perfect: high performance gains in older adults engaged in selective attention within and across sensory modalities. Acta Psychologica. 191, 101-111. (IF 1.595)
Mayrhofer HC, Duecker F, van de Ven V, Jacobs HIL, Sack AT (2018). Hemifield-specific correlations between cue-related blood oxygen level dependent activity in bilateral nodes of the dorsal attention network and attentional benefits in a spatial orienting paradigm. Journal of Cognitive Neuroscience. 21, 1-14 (IF 3.029)
van Hooren RWE, Riphagen JM, Jacobs HIL (2018). Internetwork connectivity and amyloid-beta linked to cognitive decline in preclinical Alzheimer's disease: a longitudinal cohort study. Alzheimer's Research and Therapy, 10:88 (IF 6.142)
Rosenberg J, Jacobs HIL, Maximov II, Reske M, Shah J (2018). Chronotype differences in cortical thickness: grey matter reflects when you go to bed. Brain Structure and Function, 223(7), 3411-3421 (IF 3.622)
Buckley RF, Mormino EC, Amariglio RE, Properzi MJ, Rabin JS, Lim YY, Papp KV, Jacobs HIL, Burnham S, Hanseeuw BJ, Doré V, Dobson A, Masters CL, Waller M, Rowe CC, Maruff P, Donohue MC, Rente DM, Kirn D, Hedden T, Chhatwal JP, Schultz AP, Johnson KA, Villemagne VL, Sperling RA, on behalf of collaborators in the Alzheimer's Disease Neuroimaging Initiative, the Australian Imaging Biomarker and Lifespan Study of Aging, the Harvard Aging Brain Study. (2018) Sex, amyloid and APOE-E4 and risk of cognitive decline in preclinical Alzheimer's disease: Findings from three well-characterized cohorts. Alzheimer's & Dementia, 14(9), 1193-1203 (IF 14.423)
Jacobs HIL, Müller-Ehrenberg L, Priovoulos N, Roebroeck A. (2018) Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study. Neurobiology of Aging, 69, 167-176 (IF 4.398)
Hanseeuw BJ, Betensky RA, Mormino EC, Schultz AP, Sepulcre J, Becker JA, Jacobs HIL, Buckley RF, LaPoint M, Vannini P, Donovan NJ, Chhatwal JP, Marshall GA, Papp KV, Amariglio RE, Rentz DM, Sperling RA, Johnson KA, for the Alzheimer's Disease Neuroimaging Initiative and the Harvard Aging Brain Study. (2018) PET staging of amyloidosis using striatum. Alzheimer's & Dementia, 14(10), 1281-1292 (IF 14.423)
Riphagen JM, Gronenschild EHBM, Salat DH, Freeze WM, Ivanov D, Clerx L, Verhey FRJ, Aalten P, Jacobs HIL (2018). Shades of white: diffusion properties of T1- and FLAIR defined white matter signal abnormalities differ in stages from cognitively normal to dementia. Neurobiology of Aging, 68, 48-58 (IF 4.398)
Lee CM*, Jacobs HIL*, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KA (2018). 18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus signal. Journal Of Alzheimer's Disease, 62, 1691-1702 (IF 3.517)
Jacobs HIL, Hedden T, Schultz AP, Sepulcre J, Perea RD, Amariglio RE, Papp KV, Rentz DM, Sperling RA & Johnson KA (2018). Structural tract alterations predict down-stream tau accumulation in amyloid positive older individuals. Nature Neuroscience, 21(3), 424-431 (IF 21.126)
Jacobs H.I.L., Hopkins D.A., Mayrhofer H.C., Bruner E., van Leeuwen F.W., Raaijmakers W. & Schmahmann J.D. (2017). The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline. Brain, 141(1), 37-47 (IF 11.814)
2017
Bos I., Verhey F.R., Ramakers I.H.G.B., Jacobs H.I.L., Soininen H., Freund-Levi Y., Hampel H., Tsolaki M., Wallin A.K., van Buchem M.A., Oleksik A., Verbeek M.M., Olde Rikkert M., van der Flier W.M., Scheltens F., Aalten P., Visser P.J. & Vos S.J.B. (2017). Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline. Alzheimer's Research & Therapy, 9(1), 101, (IF 6.142)
Uquillas F.O., Jacobs H.I.L., Hanseeuw B.,Marshall G.A., Properz M., Schultz A.P., LaPoint M.R., Johnson K.A., Sperling R.A. & Vannini P. (2017). Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage Clinical, 17,388-396 (IF 3.943)
Priovoulos N., Jacobs H.I.L., Ivanov D., Uludag K., Verhey F.R.J. & Poser B.A. (2017). High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T. Neuroimage, 168, 427-436 (IF 5.812)
Freeze W.M., Schnerr R.S., Palm W.M., Jansen J.F., Jacobs H.I.L., Hoff E.I., Verhey F.R.J., & Backes W.H. (2017). Pericortical enhancement on delayed postgadolinium fluid-attenuated inversion recovery images in normal aging, mild cognitive impairment, and Alzheimer's disease. American Journal of Neuroradiology, 38(9),1742-1747 (IF 3.256)
Dillen K.N.H., Jacobs H.I.L., Kukolja J., Richter N., von Reutern B., Onur Ö.A., Langen K.-J. & Fink G.R.(2017) Functional disintegration of the default mode network in prodromal Alzheimer's disease. Journal Of Alzheimer's Disease, 59(1), 169-187 (IF 3.517)
Dekhtyar M., Papp K.V., Buckley R., Jacobs H.I.L., Schultz A.P., Johnson K.A., Sperling R.A. & Rentz D.M. (2017) Neuroimaging markers associated with maintenance of optimal memory performance in late-life. Neuropsychologia, 100, 164-170 (IF 2.872)
Cleutjens F.A.H.M., Ponds R.W.H.M., Spruit M.A.,, Burgmans S., Jacobs H.I.L., Gronenschild E.H.B.M., Staals J., Franssen F.M.E., Dijkstra J.B., Vanfleteren L.E.G.W., Hofman P.A., Wouters E.F.M. & Janssen D.J..A. (2017) The relationship between cerebral small vessel disease, hippocampal volume and cognitive functioning in patients with COPD: a MRI study. Frontiers in Aging Neuroscience, 30, 9-88 (IF 3.633)
Freeze W.M., Jacobs H.I.L., Gronenschild E.H.B.M., Jansen J.F.A., Burgmans S., Aalten P., Clerx L., Vos S.J., van Buchem M.A., Barkhof F., van der Flier W.M., Verbeek M.M., Olde Rikkert M., Backes W.H. & Verhey F.R.J. (2017) White matter hyperintensities potentiate hippocampal volume reduction in non-demented older individuals with abnormal amyloid-β. Journal of Alzheimer's Disease,, 55(1), 333-342 (IF 3.517)
Uquillas F.O., Jacobs H.I.L., Hanseeuw B.,Marshall G.A., Properz M., Schultz A.P., LaPoint M.R., Johnson K.A., Sperling R.A. & Vannini P. (2017). Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals. Neuroimage Clinical, 17,388-396 (IF 3.943)
Priovoulos N., Jacobs H.I.L., Ivanov D., Uludag K., Verhey F.R.J. & Poser B.A. (2017). High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T. Neuroimage, 168, 427-436 (IF 5.812)
Freeze W.M., Schnerr R.S., Palm W.M., Jansen J.F., Jacobs H.I.L., Hoff E.I., Verhey F.R.J., & Backes W.H. (2017). Pericortical enhancement on delayed postgadolinium fluid-attenuated inversion recovery images in normal aging, mild cognitive impairment, and Alzheimer's disease. American Journal of Neuroradiology, 38(9),1742-1747 (IF 3.256)
Dillen K.N.H., Jacobs H.I.L., Kukolja J., Richter N., von Reutern B., Onur Ö.A., Langen K.-J. & Fink G.R.(2017) Functional disintegration of the default mode network in prodromal Alzheimer's disease. Journal Of Alzheimer's Disease, 59(1), 169-187 (IF 3.517)
Dekhtyar M., Papp K.V., Buckley R., Jacobs H.I.L., Schultz A.P., Johnson K.A., Sperling R.A. & Rentz D.M. (2017) Neuroimaging markers associated with maintenance of optimal memory performance in late-life. Neuropsychologia, 100, 164-170 (IF 2.872)
Cleutjens F.A.H.M., Ponds R.W.H.M., Spruit M.A.,, Burgmans S., Jacobs H.I.L., Gronenschild E.H.B.M., Staals J., Franssen F.M.E., Dijkstra J.B., Vanfleteren L.E.G.W., Hofman P.A., Wouters E.F.M. & Janssen D.J..A. (2017) The relationship between cerebral small vessel disease, hippocampal volume and cognitive functioning in patients with COPD: a MRI study. Frontiers in Aging Neuroscience, 30, 9-88 (IF 3.633)
Freeze W.M., Jacobs H.I.L., Gronenschild E.H.B.M., Jansen J.F.A., Burgmans S., Aalten P., Clerx L., Vos S.J., van Buchem M.A., Barkhof F., van der Flier W.M., Verbeek M.M., Olde Rikkert M., Backes W.H. & Verhey F.R.J. (2017) White matter hyperintensities potentiate hippocampal volume reduction in non-demented older individuals with abnormal amyloid-β. Journal of Alzheimer's Disease,, 55(1), 333-342 (IF 3.517)
2016
Dillen K.N.H., Jacobs H.I.L., Kukolja J., von Reutern B., Richter N., Onur Ö.A., Dronse J., Langen K.-J. & Fink G.R.(2016) Aberrant functional connectivity differentiates retrosplenial cortex from posterior cingulate cortex in prodromal Alzheimer’s disease. Neurobiology of Aging, 44, 114-26 (IF 4.398)
2015
Clerx, L., Gronenschild, E.H.B.M., Echavarri, C., Verhey, F.R.J., Aalten, P. & Jacobs, H.I.L. (2015) Can FreeSurfer compete with manual volumetric measurements in Alzheimer’s disease? Current Alzheimer Research, 12(4), 358-67 (IF 3.211)
Jacobs, H.I.L., Riphagen, J.M., Razat, C.M., Wiese, S. & Sack, A.T. (2015) Transcutaneous vagus nerve stimulation boosts associative memory in older individuals. Neurobiology of Aging, 36(6), 1860-7 (IF 4.398)
Jacobs, H.I.L., Dillen, K.N., Risius, O., Göreci, Y., Onur, O.A., Fink, G.R. & Kukolja, J. (2015) Consolidation in older adults depends upon competition between resting-state networks. Frontiers in Aging Neuroscience, 6, 344 (IF 3.633)
Jacobs, H.I.L., Wiese, S., van de Ven, V., Gronenschild, E.H.B.M., Verhey, F.R.J. & Matthews, P.M. (2015) Relevance of parahippocampal - locus coeruleus connectivity to memory in early dementia. Neurobiology of Aging, 36(2), 618-26 (IF 4.398)
Jacobs, H.I.L., Gronenschild, E.H.B.M., Evers, E.A.T., Ramakers, I.H.G.B., Hofman, P.A.M., Backes, W.H., Jolles, J., Verhey, F.R.J. & van Boxtel, M.P.J. (2012) Visuospatial processing in early Alzheimer’s disease: a multimodal neuroimaging study. Cortex, 64, 394-406 (IF 4.275)
Jacobs, H.I.L., Riphagen, J.M., Razat, C.M., Wiese, S. & Sack, A.T. (2015) Transcutaneous vagus nerve stimulation boosts associative memory in older individuals. Neurobiology of Aging, 36(6), 1860-7 (IF 4.398)
Jacobs, H.I.L., Dillen, K.N., Risius, O., Göreci, Y., Onur, O.A., Fink, G.R. & Kukolja, J. (2015) Consolidation in older adults depends upon competition between resting-state networks. Frontiers in Aging Neuroscience, 6, 344 (IF 3.633)
Jacobs, H.I.L., Wiese, S., van de Ven, V., Gronenschild, E.H.B.M., Verhey, F.R.J. & Matthews, P.M. (2015) Relevance of parahippocampal - locus coeruleus connectivity to memory in early dementia. Neurobiology of Aging, 36(2), 618-26 (IF 4.398)
Jacobs, H.I.L., Gronenschild, E.H.B.M., Evers, E.A.T., Ramakers, I.H.G.B., Hofman, P.A.M., Backes, W.H., Jolles, J., Verhey, F.R.J. & van Boxtel, M.P.J. (2012) Visuospatial processing in early Alzheimer’s disease: a multimodal neuroimaging study. Cortex, 64, 394-406 (IF 4.275)
2014
Lückmann H., Jacobs, H.I.L. & Sack, A.T. (2014) The cross-functional role of frontoparietal regions in cognition - Internal attention as the overarching mechanism. Progress in Neurobiology, 116, 66-86 (IF 10.658)
Bruner, E., Rangel de Låzaro, G., de la Cuétara, J.M., Martin-Loeches, M., Colom, R. & Jacobs, H.I.L. (2014) Midsaggital brain variation and MRI shape analysis of the precuneus in adult individuals. Journal of Anatomy,224(4), 367-76 (IF 2.638)
Jacobs, H.I.L., Clerx, L., Gronenschild, E.H.B.M., Aalten, P. & Verhey, F.R.J. (2014) White matter hyperintensities are positively associated with cortical thickness in Alzheimer’s disease. Journal of Alzheimer’s Disease, 39(2), 409-22 (IF 3.517).
Bruner, E., Rangel de Låzaro, G., de la Cuétara, J.M., Martin-Loeches, M., Colom, R. & Jacobs, H.I.L. (2014) Midsaggital brain variation and MRI shape analysis of the precuneus in adult individuals. Journal of Anatomy,224(4), 367-76 (IF 2.638)
Jacobs, H.I.L., Clerx, L., Gronenschild, E.H.B.M., Aalten, P. & Verhey, F.R.J. (2014) White matter hyperintensities are positively associated with cortical thickness in Alzheimer’s disease. Journal of Alzheimer’s Disease, 39(2), 409-22 (IF 3.517).
2013
Clerx, L., Jacobs, H.I.L., Burgmans S., Gronenschild E.H.B.M., Uylings, H.B.M., Echávarri, C., Visser, P.J., Verhey, F.R.J. & Aalten, P. (2013) Sensitivity of different MRI-techniques to assess gray matter atrophy patterns in Alzheimer’s disease is region-specific. Current Alzheimer Research, 10(9), 940-951(IF 3.211)
Jacobs, H.I.L., Radua, J., Lückmann, H. & Sack, A. (2013) Meta-analysis of functional network alterations in Alzheimer’s disease: towards a network biomarker. Neuroscience and Biobehavioral Reviews, 37(5), 753-765 (IF 8.002)
Bruner E*. & Jacobs, H.I.L.* (2013) Alzheimer’s disease: the downside of a highly evolved parietal lobe? Journal of Alzheimer’s Disease, 35(2), 227-240 (IF 3.517)
Mills, J.M., Nalpathamkalam, T., Jacobs, H.I.L., Janitz, C., Merico, D., Hu, P. & Janitz, M. (2013) RNA-Seq analysis of the parietal cortex in Alzheimer’s disease reveals alternatively spliced isoforms related to lipid metabolism. Neuroscience Letters, 536, 90-95 (IF 2.173)
Jacobs, H.I.L., Leritz, E.C., Williams, V.J., Van Boxtel, M.P.J. van der Elst, W., Jolles, J. & Verhey, F.R.J., McGlinchey, R.E., Milberg, W.P., & Salat, D.H. (2013). Association between white matter microstructure and cognition in older adults : the impact of vascular health. Human Brain Mapping, 34(1), 77-95 (IF 4.554)
Jacobs, H.I.L., Van Boxtel, M.P.J., Gronenschild, E.H.B.M., Uylings, H.B.M., Jolles, J. & Verhey, F.R.J. (2013) Decreased gray matter diffusivity: a potential early Alzheimer disease biomarker? Alzheimer’s & Dementia, 9(1), 93-97 (IF 14.423)
Jacobs, H.I.L., Radua, J., Lückmann, H. & Sack, A. (2013) Meta-analysis of functional network alterations in Alzheimer’s disease: towards a network biomarker. Neuroscience and Biobehavioral Reviews, 37(5), 753-765 (IF 8.002)
Bruner E*. & Jacobs, H.I.L.* (2013) Alzheimer’s disease: the downside of a highly evolved parietal lobe? Journal of Alzheimer’s Disease, 35(2), 227-240 (IF 3.517)
Mills, J.M., Nalpathamkalam, T., Jacobs, H.I.L., Janitz, C., Merico, D., Hu, P. & Janitz, M. (2013) RNA-Seq analysis of the parietal cortex in Alzheimer’s disease reveals alternatively spliced isoforms related to lipid metabolism. Neuroscience Letters, 536, 90-95 (IF 2.173)
Jacobs, H.I.L., Leritz, E.C., Williams, V.J., Van Boxtel, M.P.J. van der Elst, W., Jolles, J. & Verhey, F.R.J., McGlinchey, R.E., Milberg, W.P., & Salat, D.H. (2013). Association between white matter microstructure and cognition in older adults : the impact of vascular health. Human Brain Mapping, 34(1), 77-95 (IF 4.554)
Jacobs, H.I.L., Van Boxtel, M.P.J., Gronenschild, E.H.B.M., Uylings, H.B.M., Jolles, J. & Verhey, F.R.J. (2013) Decreased gray matter diffusivity: a potential early Alzheimer disease biomarker? Alzheimer’s & Dementia, 9(1), 93-97 (IF 14.423)
2012
Jacobs, H.I.L., Van Boxtel, M.P.J., Heinecke, A., Gronenschild, E.H.B.M., Backes, W.H., Jolles, J. & Verhey, F.R.J. (2012) Functional integration of parietal lobe activity in early Alzheimer's disease. Neurology, 78, 352-360 (IF 8.689)
Gronenschild, E.H.B.M., Habets, P., Jacobs, H.I.L., Mengelers,R., Rozendaal, N., van Os, J. & Marcelis, M. (2012) The effects of FreeSurfer version, workstation type, and Macintosh operating system version on neuroanatomical volume and cortical thickness measurements. PLoS ONE, 7(6), e38234 (IF 2.776)
Jacobs, H.I.L., van Boxtel, M.P.J., Gronenschild E.H.B.M., Williams V.J., Uylings, H.B.M., Burgmans, S., Jolles, J. & Verhey, F.R.J. (2012) Patterns of grey and white matter changes in individuals at risk for Alzheimer’s disease. Current Alzheimer Research, 9(9), 1097-1105(IF 3.211)
Jacobs, H.I.L., van Boxtel, M.P.J., Jolles, J., Verhey, F.R. & Uylings, H.B.M. (2012). Parietal cortex matters in early Alzheimer’s Disease: an overview of structural, functional and metabolic findings. Neuroscience and Biobehavioral Reviews, 36(1), 297-309 (IF 8.002)
Jacobs, H.I.L., Visser, P.J., van Boxtel, M.P.J., Jolles, J. & Verhey, F.R.J. and members of the Descripa study. (2012). The association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent. Neurobiology of Aging, 33(1), 201.e201-208 (IF 4.398)
Gronenschild, E.H.B.M., Habets, P., Jacobs, H.I.L., Mengelers,R., Rozendaal, N., van Os, J. & Marcelis, M. (2012) The effects of FreeSurfer version, workstation type, and Macintosh operating system version on neuroanatomical volume and cortical thickness measurements. PLoS ONE, 7(6), e38234 (IF 2.776)
Jacobs, H.I.L., van Boxtel, M.P.J., Gronenschild E.H.B.M., Williams V.J., Uylings, H.B.M., Burgmans, S., Jolles, J. & Verhey, F.R.J. (2012) Patterns of grey and white matter changes in individuals at risk for Alzheimer’s disease. Current Alzheimer Research, 9(9), 1097-1105(IF 3.211)
Jacobs, H.I.L., van Boxtel, M.P.J., Jolles, J., Verhey, F.R. & Uylings, H.B.M. (2012). Parietal cortex matters in early Alzheimer’s Disease: an overview of structural, functional and metabolic findings. Neuroscience and Biobehavioral Reviews, 36(1), 297-309 (IF 8.002)
Jacobs, H.I.L., Visser, P.J., van Boxtel, M.P.J., Jolles, J. & Verhey, F.R.J. and members of the Descripa study. (2012). The association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent. Neurobiology of Aging, 33(1), 201.e201-208 (IF 4.398)
2011
Jacobs, H.I.L., van Boxtel, M.P.J., Uylings, H.B.M., Gronenschild, E.H.B.M., Verhey, F.R.J., & Jolles, J. (2011) Atrophy of the parietal lobe in preclinical dementia. Brain and Cognition,75(2), 154-163 (IF 3.622)
Jacobs, H.I.L.,Van Boxtel, M.P.J. van der Elst, W.,Burgmans, S., Smeets, F., Gronenschild, E.H.B.M., Verhey, F.R., Uyling, H.B.M. & Jolles J.(2011). Increasing the diagnostic accuracy of the medial temporal lobe atrophy in Alzheimer’s Disease. Journal of Alzheimer’s Disease, 25, 477-490 (IF 3.517)
Echávarri, C., Aalten, P., Uylings, H.B.M., Jacobs, H.I.L., Visser, P.J., Gronenschild, E.H.B.M., Verhey, F.R.J., & Burgmans, S. (2011) Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer’s disease. Brain Structure and Function, 215(3-4), 265-71 (IF 3.622)
Burgmans, S., van Boxtel, M.P.J., van den Berg, K.E.M., Gronenschild, E.H.B.M, Jacobs, H.I.L., Jolles, J., & Uylings, H.B.M. (2011). The posterior parahippocampal gyrus is preferentially affected in age-related memory decline. Neurobiology of Aging, 32(9), 1572-1578 (IF 4.398)
Jacobs, H.I.L.,Van Boxtel, M.P.J. van der Elst, W.,Burgmans, S., Smeets, F., Gronenschild, E.H.B.M., Verhey, F.R., Uyling, H.B.M. & Jolles J.(2011). Increasing the diagnostic accuracy of the medial temporal lobe atrophy in Alzheimer’s Disease. Journal of Alzheimer’s Disease, 25, 477-490 (IF 3.517)
Echávarri, C., Aalten, P., Uylings, H.B.M., Jacobs, H.I.L., Visser, P.J., Gronenschild, E.H.B.M., Verhey, F.R.J., & Burgmans, S. (2011) Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer’s disease. Brain Structure and Function, 215(3-4), 265-71 (IF 3.622)
Burgmans, S., van Boxtel, M.P.J., van den Berg, K.E.M., Gronenschild, E.H.B.M, Jacobs, H.I.L., Jolles, J., & Uylings, H.B.M. (2011). The posterior parahippocampal gyrus is preferentially affected in age-related memory decline. Neurobiology of Aging, 32(9), 1572-1578 (IF 4.398)
Aggregate Impact factor for my own field (ISI Web of Knowledge, journal citation reports 2018):
• Neurosciences 4.035
• Psychology 2.831
• Neuroimaging 4.119
Average impact factor of my own publications
• First-author publications: 7.154
• All publications: 6.287
(Total impact factor: 427.52)
Google Scholar Citations Metrics
• Neurosciences 4.035
• Psychology 2.831
• Neuroimaging 4.119
Average impact factor of my own publications
• First-author publications: 7.154
• All publications: 6.287
(Total impact factor: 427.52)
Google Scholar Citations Metrics
Books & Chapters in books
Jacobs H.I.L. (2011) Parietal matters in early Alzheimer's disease: evidence from structural and functional MRI. Maastricht: Maastricht University (dissertation).
National publications
Jacobs, H.I.L. (2013). Functional integration of parietal lobe activity in early Alzheimer’s disease: findings and implications. Klinische Neurophysiologie,44(1), 28-32
Jacobs, H.I.L. (2011). De rol van de parietaalkwab in de vroege fase van de ziekte van Alzheimer. Neuropraxis, 15(4), 113-120